Letrozole Tablets USP 2.5 mg
Price range: $90.00 through $140.00
| Quantity Value | Price | Price/Unit | Quantity | Add To Cart |
|---|---|---|---|---|
| 100 Tablet S | $90.00 | $0.90 / Piece |
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| 200 Tablets | $140.00 | $0.70 / Piece |
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SKU : N/A
Category : Other
Letrozole Tablets USP 2.5 mg
Letrozole Tablets USP 2.5 mg contain letrozole, a prescription medicine belonging to a group of drugs called aromatase inhibitors. Letrozole is primarily used as hormonal therapy for certain types of breast cancer in postmenopausal women. It lowers the amount of estrogen produced by the body, which can help slow or stop the growth of estrogen-dependent cancer cells.
Letrozole may be prescribed after surgery or other initial treatment to reduce the risk of breast cancer returning. It may also be used for advanced or metastatic hormone-sensitive breast cancer. In some reproductive-health settings, letrozole is also prescribed off-label to stimulate ovulation, particularly in women with certain types of infertility.
Uses of Letrozole 2.5 mg
Letrozole is mainly used for the treatment of hormone receptor-positive breast cancer in postmenopausal women. Depending on the clinical situation, it may be prescribed:
- As adjuvant treatment after surgery for early breast cancer
- As extended hormonal treatment following previous therapy such as tamoxifen
- For locally advanced or metastatic hormone-sensitive breast cancer
- In certain cases to reduce the risk of recurrence
- For ovulation induction in selected women with infertility, under specialist supervision
The appropriate use depends on the patient’s age, menopausal status, cancer characteristics, previous treatments, and overall health.
How Letrozole Works
Letrozole works by inhibiting aromatase, an enzyme responsible for converting androgens into estrogen.
After menopause, most estrogen is produced through this conversion process rather than directly by the ovaries. By blocking aromatase, letrozole substantially lowers estrogen levels.
Some breast cancer cells use estrogen as a growth signal. Reducing estrogen availability can therefore slow the growth of hormone-sensitive cancer cells and help reduce the likelihood of recurrence in appropriate patients.
How to Take Letrozole 2.5 mg
The usual dose for breast cancer treatment is 2.5 mg once daily, although the exact dose and duration must be determined by the treating healthcare professional.
Letrozole can generally be taken with or without food. Take the tablet at approximately the same time each day and swallow it with water.
If you forget a dose, take it when remembered unless it is nearly time for the next scheduled dose. Do not take two tablets together to compensate for a missed dose.
For cancer treatment, letrozole may be taken for several years depending on the treatment plan. Do not discontinue therapy without discussing it with your oncologist.
When letrozole is used for ovulation induction, the dosage and timing are different and must be determined by a fertility specialist.
Common Side Effects
Because letrozole reduces estrogen levels, many side effects resemble symptoms associated with menopause. Possible adverse effects include:
- Hot flushes and sweating
- Joint, muscle, or bone pain
- Tiredness and weakness
- Headache
- Dizziness
- Nausea
- Increased sweating
- Sleep disturbances
- Mood changes
- Vaginal dryness
- Increased cholesterol levels
Some people experience joint stiffness or pain that may affect daily activities. Persistent or severe symptoms should be discussed with a healthcare professional.
Bone Health
Long-term estrogen reduction can contribute to bone thinning and osteoporosis. This may increase the risk of fractures, particularly in patients who already have reduced bone density.
Doctors may recommend a bone mineral density assessment before or during treatment. Depending on individual risk, calcium and vitamin D intake, weight-bearing exercise, lifestyle measures, or medicines designed to protect bone health may be recommended.
Letrozole can also increase cholesterol levels in some patients, so cholesterol monitoring may be appropriate.
Precautions and Warnings
Letrozole is primarily intended for postmenopausal women when used for breast cancer treatment. It should not be used during pregnancy because it may cause fetal harm.
Women who are pregnant, planning pregnancy, or who could become pregnant should discuss appropriate precautions with their healthcare professional. When letrozole is used for fertility treatment, pregnancy should be confirmed or excluded according to the fertility specialist’s instructions before subsequent treatment.
Tell your doctor if you have:
- Osteoporosis or a history of fractures
- High cholesterol
- Liver disease
- Kidney disease
- Cardiovascular disease
- Unexplained vaginal bleeding
- Previous medication allergies
Letrozole may cause dizziness or fatigue in some patients. Avoid driving or operating machinery if you feel impaired.
Drug Interactions
Letrozole may interact with certain medicines, including some estrogen-containing treatments. Estrogen-containing medicines may reduce the effectiveness of letrozole when it is being used for hormone-sensitive breast cancer.
Always provide your healthcare professional with a complete list of prescription medicines, over-the-counter products, vitamins, and herbal supplements you use.
Storage
Store Letrozole Tablets USP 2.5 mg at room temperature in a dry place, protected from excessive heat and moisture. Keep the tablets in their original packaging and out of reach of children.
Do not use tablets after the expiration date printed on the packaging.
Conclusion
Letrozole Tablets USP 2.5 mg are an important hormonal treatment for postmenopausal women with certain estrogen-sensitive breast cancers. By inhibiting aromatase and reducing estrogen production, letrozole can help slow cancer growth and lower the risk of recurrence in appropriate patients.
Because prolonged estrogen suppression can affect bones, joints, cholesterol, and overall well-being, regular medical follow-up is important during treatment. Letrozole should be taken exactly as prescribed, and patients should discuss significant or persistent side effects with their healthcare professional rather than stopping treatment independently.
| Pack Size |
100 Tablet/s ,200 Tablets |
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