Name: Seroflo Ciphaler 500 mcg – Asthma & COPD Inhalation Relief
Availability: InStock

Introduction

Living with chronic respiratory diseases like asthma or chronic obstructive pulmonary disease (COPD) can significantly affect a person’s quality of life. To manage such conditions effectively, medical science has developed combination therapies that target both inflammation and airway constriction. One such trusted and effective combination is Seroflo Ciphaler 500 mcg.

Seroflo Ciphaler 500 mcg is a dry powder inhaler (DPI) that combines two essential drugs: Salmeterol (a long-acting bronchodilator) and Fluticasone Propionate (a corticosteroid). This medication helps patients manage asthma and COPD by providing dual-action relief, opening up airways and reducing inflammation.

Composition and Strength

Seroflo Ciphaler 500 mcg doses include:

Salmeterol Xinafoate equivalent to Salmeterol 50 mcg
Fluticasone Propionate 500 mcg

These medications are formulated as a dry powder for inhalation using a Ciphaler device, which delivers a metered dose directly into the lungs.

Pharmacological Classification

Salmeterol: Long-acting beta-2 adrenergic receptor agonist (LABA)
Fluticasone Propionate: Inhaled corticosteroid (ICS)

This combination targets both the bronchoconstriction and inflammatory components of asthma and COPD.

Mechanism of Action

Salmeterol (50 mcg)

Salmeterol is a LABA that works by stimulating beta-2 receptors in the smooth muscles of the airways. This stimulation causes the muscles to relax, which opens up the air passages and makes breathing easier. The effect lasts for approximately 12 hours, making it suitable for twice-daily use.

Fluticasone Propionate (500 mcg)

A strong corticosteroid that lowers inflammation in the bronchial passages is fluticasone. It works by inhibiting multiple types of inflammatory cells and mediators, thus decreasing mucus production, airway swelling, and hyper-responsiveness to allergens and irritants.

Together, this combination:

Prevents asthma attacks
Reduces the frequency of COPD exacerbations
Improves lung function and overall respiratory health

Indications

Seroflo Ciphaler 500 mcg is prescribed for the long-term management of:

1. Bronchial Asthma

In patients who require both bronchodilator and anti-inflammatory therapy
Suitable for moderate to severe persistent asthma
Helps reduce reliance on rescue inhalers

2. Chronic Obstructive Pulmonary Disease (COPD)

Especially effective in patients with frequent symptoms and exacerbations
lowers hospital visits and enhances quality of life
Reduces breathlessness, cough, and wheezing

Dosage and Administration

Adult and adolescent dosage recommendations (12+ years):

One inhalation twice daily—morning and evening

This fixed-dose combination is not intended for acute symptom relief. For sudden symptoms or asthma attacks, a short-acting beta agonist (SABA) like salbutamol should be used.

Instructions for Use:

Open the cap while holding the Ciphaler upright.
Depending on the design, either rotate the mouthpiece or insert a capsule.
Exhale fully away from the device.
Put the mouthpiece in your mouth and take a strong, deep breath.
Take the gadget off, then hold your breath for ten seconds.
To prevent oral infections, rinse your mouth with water after using it.

Benefits of Seroflo Ciphaler 500 mcg

✅ Long-Acting Relief

One dose provides bronchodilation and anti-inflammatory action for up to 12 hours.

✅ Dual Mechanism

Targets both the root cause (inflammation) and symptoms (bronchospasm) of respiratory diseases.

✅ Reduces Dependence on Oral Steroids

Safer and more effective in the long term compared to systemic corticosteroids.

✅ Improves Daily Functioning

Helps patients resume regular activities, improve sleep, and maintain a better quality of life.

✅ Easy-to-Use Device

Ciphaler is a portable, breath-actuated device suitable for long-term use with proper technique.

Precautions and Warnings

⚠️ General Warnings

Not for use in acute asthma attacks
Not appropriate for mild asthma as a first-line treatment
Use with caution in patients with cardiovascular disease, thyroid dysfunction, or diabetes

⚠️ During Pregnancy and Lactation

Use only if clearly needed and prescribed by a physician

⚠️ Pediatric Use

Lower doses may be prescribed for children. This specific strength (500 mcg) is not recommended for children under 12.

Possible Side Effects

Most side effects are mild and can be minimized with correct inhalation technique and mouth rinsing.

Common Side Effects

Headache
Hoarseness
Sore throat
Oral candidiasis (fungal infection)
Nausea

Less Common but Serious Side Effects

Palpitations
Muscle cramps
Tremors
Signs of adrenal suppression
Worsening asthma symptoms
Paradoxical bronchospasm (rare)

Seek immediate medical attention for:

Allergic reactions (rash, itching, swelling)
Sudden breathing difficulties

Drug Interactions

Let your physician know if you are taking:

Beta-blockers (may reduce the effectiveness of salmeterol)
MAO inhibitors or tricyclic antidepressants
Antifungals (e.g., ketoconazole) or HIV protease inhibitors
Diuretics may make low potassium levels more likely.

Missed Dose and Overdose

Missed Dose

Take the missed dose as soon as you remember, unless it’s nearly time for your next dose.
Never double-dose.

Overdose Symptoms

Fast heart rate
Tremors
Chest pain
Muscle weakness

If you suspect an overdose, get medical attention right away.

Storage Instructions

Store below 30°C in a dry place
Do not freeze
Keep away from direct sunlight and moisture
Keep out of reach of children

Patient Counseling Tips

Emphasize adherence to twice-daily dosing for maximum benefit.
Instruct on proper inhalation technique to ensure drug effectiveness.
Recommend mouth rinsing post-inhalation to prevent oral thrush.
Discuss the importance of monitoring asthma control through peak flow meters or symptoms.
Educate patients that Seroflo is not a rescue inhaler.

Frequently Asked Questions (FAQs)

1. Is Seroflo Ciphaler 500 mcg addictive?

No. It is not habit-forming. It is a maintenance therapy designed for long-term control of asthma and COPD.

2. Can I stop using it once I feel better?

No. Continue use unless instructed otherwise by your doctor. Stopping suddenly can cause a return of symptoms.

3. How long before it starts working?

Some symptom relief may be noticeable within a few days, but full benefits develop over 1–2 weeks of consistent use.

4. Can it be used with a spacer?

No. Ciphaler is a dry powder inhaler (DPI), which doesn’t require or work with spacers.

5. What should I do if I get oral thrush?

Consult your doctor. You may need antifungal treatment. Prevent it by rinsing your mouth after each dose.

Conclusion

Seroflo Ciphaler 500 mcg offers a powerful and effective treatment option for patients suffering from asthma and COPD. With its dual-action mechanism combining Salmeterol and Fluticasone, it reduces symptoms, prevents exacerbations, and helps patients lead healthier, more active lives.

Proper usage, adherence to dosing schedules, and regular follow-ups with your healthcare provider are key to achieving the best therapeutic outcomes.

Whether you’re managing moderate to severe asthma or combating the daily struggles of COPD, Seroflo Ciphaler 500 mcg remains a trusted and clinically effective choice in inhalation therapy.

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Quantity Value	Price	Quantity	Add To Cart
1 Multihaler	$45.00
2 Multihaler	$84.00
3 Multihaler	$117.00

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Seroflo Ciphaler 500 mcg