Pirfenex 400 Mg
Price range: $70.00 through $1,800.00
| Quantity Value | Price | Quantity | Add To Cart |
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| 10 Tablet/s | $70.00 |
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| 30 Tablet/s | $135.00 |
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| 50 Tablet/s | $150.00 |
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| 100 Tablet/s | $270.00 |
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| 200 Tablet/s | $500.00 |
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| 300 Tablet/s | $660.00 |
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| 500 Tablet/s | $1,000.00 |
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| 1000 Tablet/s | $1,800.00 |
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SKU : Pirfenex 400 Mg
Category : Pirfenidone , Viral Care
Pirfenex 400 Mg is used to manage idiopathic pulmonary fibrosis (IPF). It helps reduce lung scarring, slow disease progression, and improve breathing.
Pirfenex 400 mg Tablet is a powerful pharmaceutical formulation specifically designed for patients suffering from Idiopathic Pulmonary Fibrosis (IPF). This progressive, chronic condition causes irreversible scarring in the lungs, which leads to breathlessness and a decrease in oxygen transfer to the bloodstream. a medication that has become a cornerstone in IPF treatment due to its anti-fibrotic and anti-inflammatory properties. With its higher strength per tablet (400 mg), this formulation is especially useful in reducing daily pill burden and enhancing patient compliance.
The 400 mg dosage strength allows for fewer tablets per day compared to the lower-strength variants, making it ideal for long-term management of IPF in patients requiring higher daily doses. Pirfenex 400 mg has improved the lives of many by offering relief from symptoms, slowing disease progression, and giving patients better control over their respiratory health.
Understanding Idiopathic Pulmonary Fibrosis (IPF)
IPF is a rare yet serious condition characterized by chronic, progressive lung scarring (fibrosis) of unknown origin. The lung tissue becomes thick and stiff, preventing the lungs from functioning efficiently. Over time, this leads to shortness of breath, chronic cough, reduced stamina, and eventually respiratory failure.
As IPF progresses, the lungs lose their ability to efficiently transfer oxygen to the blood. The disease severely impacts a person’s quality of life, often limiting physical activities and independence. There is currently no cure for IPF, but early and effective treatment with medications like Pirfenex can significantly slow disease progression and improve symptoms.
What is Pirfenex 400 mg?
Pirfenex 400 mg contains Pirfenidone, a medication proven to slow the scarring process in IPF. It helps protect lung function over time and reduces the rapid decline seen in untreated patients. Pirfenidone works by targeting various biological pathways that contribute to fibrosis and inflammation.
The 400 mg strength formulation offers a convenient way to meet the full daily dosage requirement with fewer tablets, which makes it easier for patients to maintain adherence and consistency in treatment.
How Pirfenex 400 mg Works
Pirfenidone, the active ingredient in Pirfenex 400 mg, has a dual-action mechanism:
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Anti-fibrotic Action: It suppresses the activity of pro-fibrotic growth factors such as transforming growth factor-beta (TGF-β), which are responsible for the abnormal build-up of fibrous tissue in the lungs.
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Anti-inflammatory Action: It also inhibits the production of inflammatory mediators like tumor necrosis factor-alpha (TNF-α), which contribute to chronic inflammation and further tissue damage.
By addressing both fibrosis and inflammation, Pirfenex 400 mg slows the progression of IPF, helping patients breathe better and retain lung function for a longer duration.
Indications
Pirfenex 400 mg is indicated for:
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Idiopathic Pulmonary Fibrosis (IPF) – to reduce disease progression, delay lung function deterioration, and improve the patient’s ability to perform daily activities.
It may also be explored for use in fibrotic interstitial lung diseases and other lung disorders associated with fibrosis under medical supervision, although these uses are considered off-label.
Dosage and Administration
Standard Dosage for IPF:
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The total recommended daily dose is 2400 mg of Pirfenidone, divided into three doses of 800 mg each.
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Using the 400 mg strength, patients typically take two tablets (800 mg) three times daily, with meals.
Dose Titration (Initial Week of Therapy):
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Week 1: One 400 mg tablet, three times a day
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Week 2: Two 400 mg tablets (800 mg), three times a day
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Week 3 and onward: Full dose, three doses of 800 mg daily (i.e., six 400 mg tablets/day)
Administration Tips:
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Always take Pirfenex with food to reduce the risk of nausea and stomach discomfort.
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Swallow the tablets whole with water. Do not chew, crush, or break them.
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Try to take doses at consistent times daily to maintain steady blood levels.
Benefits of Pirfenex 400 mg
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Slows progression of IPF
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Improves respiratory function
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Reduces symptoms like breathlessness and fatigue
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Delays disease-related complications
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Fewer tablets compared to 200 mg version
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Improves long-term survival
With consistent use, Pirfenex 400 mg can significantly delay the need for supplemental oxygen and improve a patient’s ability to remain active.
Side Effects
Pirfenex 400 mg, like all medications, can cause side effects. Most are mild to moderate and can be managed with dose adjustments or supportive care.
Common Side Effects:
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Nausea
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Vomiting
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Loss of appetite
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Diarrhea
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Weight loss
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Drowsiness or fatigue
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Rash or skin sensitivity
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Headache
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Heartburn
Serious but Rare Side Effects:
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Liver enzyme elevation
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Severe allergic reactions
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Photosensitivity or severe sunburn
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Breathing difficulties not related to IPF
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Inflammation of the liver
Patients are advised to inform their doctor if they notice persistent or severe symptoms.
Precautions and Warnings
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Liver Monitoring: Regular liver function tests are required during treatment to prevent liver damage.
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Sun Protection: Use sunscreen, sunglasses, and protective clothing, as Pirfenidone can cause photosensitivity reactions.
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Smoking: Smoking may reduce the efficacy of the medication. Patients are strongly encouraged to quit.
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Alcohol: Avoid excessive alcohol consumption to reduce the risk of liver toxicity.
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Pregnancy & Breastfeeding: Use only if clearly needed under physician advice, as safety data is limited.
Drug Interactions
Pirfenex 400 mg can interact with other medications. Some interactions may increase the risk of side effects, while others can reduce the drug’s effectiveness.
Medications to avoid or use cautiously with Pirfenex:
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Fluvoxamine
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Ciprofloxacin
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Rifampin
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Omeprazole and other enzyme inducers/inhibitors
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Blood thinners and anti-inflammatory medications
Always provide a complete list of medications to your healthcare provider, including over-the-counter drugs and supplements.
Storage Instructions
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Store in a cool, dry place at room temperature (15–30°C).
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Keep the tablets in their original packaging.
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Protect from moisture and direct sunlight.
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Keep out of reach of children and pets.
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Do not use tablets beyond their expiration date.
Patient Lifestyle and Support Tips
Managing IPF with Pirfenex 400 mg is not only about taking medication—it also involves supportive lifestyle changes to improve overall health and comfort.
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Stay Physically Active: Gentle exercises and pulmonary rehab programs can help.
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Eat Nutritiously: Maintain body weight and muscle strength with a balanced diet.
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Stay Hydrated: Especially if experiencing side effects like diarrhea or nausea.
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Avoid Infections: Stay up-to-date with vaccines and avoid crowded places during flu season.
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Regular Checkups: Monitor lung function and liver health regularly.
Why Choose Pirfenex 400 mg?
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Manufactured by a reputable pharmaceutical company
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Higher strength reduces daily tablet intake
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Clinically proven active ingredient (Pirfenidone)
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Trusted by physicians for long-term IPF management
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Helps extend and improve quality of life for IPF patients
Conclusion
Pirfenex 400 mg Tablet is an essential medication for patients diagnosed with idiopathic pulmonary fibrosis. It provides a dual benefit—slowing the progression of lung scarring and reducing inflammation—both of which are vital to preserving lung function and maintaining a better quality of life.
The 400 mg strength offers practical convenience and enhanced adherence for those on higher-dose therapy. With consistent use, medical supervision, and supportive care, Pirfenex 400 mg can play a life-changing role in the journey of those battling IPF.
Always take Pirfenex exactly as prescribed by your doctor, attend regular follow-ups, and report any new symptoms promptly to ensure safe and effective treatment outcomes.
| Quantity Value |
10 Tablet/s ,100 Tablet/s ,1000 Tablet/s ,200 Tablet/s ,30 Tablet/s ,300 Tablet/s ,50 Tablet/s ,500 Tablet/s |
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