Afatinib 40 mg
$1,322.00
SKU : N/A
Category : Cancer
Afatinib 40 mg is an oral targeted therapy containing afatinib, used under medical supervision to treat EGFR-positive non-small cell lung cancer.
Product Overview
Afatinib 40 mg is a prescription medication primarily used in the treatment of certain types of non-small cell lung cancer (NSCLC) that have specific genetic mutations in the epidermal growth factor receptor (EGFR). It belongs to a class of targeted therapies known as tyrosine kinase inhibitors (TKIs), which are designed to interfere with the growth and spread of cancer cells. Afatinib is intended for patients who require a therapy guided by molecular diagnostics and should be taken under the supervision of an oncologist or healthcare professional.
How It Works
Afatinib 40 mg works by blocking the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), which are proteins involved in signaling pathways that regulate cell growth and survival. In certain cancers, these receptors are overactive or mutated, leading to uncontrolled cell proliferation. By inhibiting these receptors, afatinib helps slow down tumor growth and can reduce the spread of cancer cells. This targeted mechanism allows for a more focused approach compared to traditional chemotherapy, though it still requires careful medical monitoring due to potential side effects.
Uses / Indications
Afatinib 40 mg is mainly prescribed for the treatment of adults with metastatic non-small cell lung cancer (NSCLC) that has specific EGFR mutations, such as exon 19 deletions or exon 21 L858R substitution mutations. It may also be considered for other EGFR-positive cancers as determined by a healthcare professional. Afatinib is not indicated for general use in cancers without confirmed EGFR mutations, emphasizing the importance of diagnostic testing before initiation.
Composition
The active ingredient in this medicine is Afatinib, available in an oral tablet formulation at a dosage of 40 mg. Each tablet contains the active pharmaceutical ingredient designed to provide consistent and controlled therapeutic effects. Inactive excipients may include compounds to ensure tablet stability and absorption, but these vary by manufacturer.
Administration
Afatinib 40 mg is administered orally, usually once daily, with or without food, as directed by a physician. It is critical to follow prescribed instructions, including timing and dosing, to maximize efficacy and minimize side effects. Patients should not alter the dosage without consulting their healthcare provider. Routine medical supervision is essential, including monitoring for side effects, liver function, and overall treatment response.
Storage Instructions
Store Afatinib tablets in a cool, dry place away from direct sunlight and moisture. Keep the medication in its original container with the lid tightly closed and out of reach of children. Avoid storing in bathrooms or areas with high humidity, as this may reduce the stability of the medicine.
Important Information / Warning
Afatinib 40 mg should only be used under the guidance of a qualified healthcare professional. Patients should inform their doctor of any pre-existing conditions, allergies, or medications, as Afatinib may interact with other treatments. Common side effects may include diarrhea, rash, stomatitis, and nail inflammation, while more serious adverse events may require dose adjustment or discontinuation. Pregnant or breastfeeding individuals should not use this medication unless specifically advised by a doctor. For detailed safety information, visit FDA Afatinib Information.
| Pack Size |
28 Tablets |
|---|
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