Lidocaine & Prilocaine Gel 10 gm

Lidocaine-Prilocaine Gel 10 gm is a highly effective topical anesthetic gel used to temporarily numb the skin and surrounding tissues. This product is formulated with two active ingredients—lidocaine and prilocaine—which work together to deliver rapid and long-lasting relief from pain and discomfort. Commonly used in dermatological, cosmetic, and minor surgical procedures, this gel is trusted by healthcare professionals to reduce patient anxiety, discomfort, and procedural pain.

With a combined 5% concentration (2.5% lidocaine and 2.5% prilocaine), Lidocaine-Prilocaine Gel is particularly suitable for procedures like needle insertions, minor skin surgeries, tattooing, laser treatments, and hair removal. Its convenient gel form allows for easy application and fast absorption, making it a go-to solution for both medical professionals and individuals seeking at-home relief for skin irritations.

Composition

Each 10 gm tube of Lidocaine-Prilocaine Gel contains:

• Lidocaine (2.5%): A fast-acting local anesthetic that numbs the skin by blocking nerve signals.

• Prilocaine (2.5%): A complementary anesthetic that enhances the efficacy of lidocaine and extends the numbing effect.

This balanced combination ensures a synergistic effect, providing a more consistent and reliable anesthetic response than either component alone.

Mechanism of Action

Lidocaine and prilocaine are amide-type local anesthetics that work by inhibiting voltage-gated sodium channels in the neuronal membrane. When applied to the skin, these agents prevent the generation and transmission of nerve impulses, resulting in temporary loss of sensation in the treated area.

By working in tandem, lidocaine and prilocaine provide a quicker onset and more prolonged duration of action than single-agent formulations. The gel begins to take effect within 30 to 60 minutes of application and can last up to two hours, depending on the thickness of the skin and the amount applied.

Indications

Lidocaine-Prilocaine Gel is indicated for a wide variety of clinical and non-clinical uses, including:

• Before Minor Surgical Procedures: Such as mole removal, skin biopsies, and minor suturing.

• Cosmetic Treatments: Laser hair removal, microdermabrasion, microneedling, and facial injections.

• Tattooing and Piercings: Reduces pain during tattoo application and ear/body piercings.

• Vaccinations and Blood Draws: Minimizes needle pain in adults and children.

• Dermatological Conditions: Eases discomfort from eczema flare-ups, insect bites, and superficial wounds.

• Personal Care Use: Occasionally used to ease pain during waxing or epilation.

How to Use

Step-by-Step Application:

1. Clean the Skin: Wash and dry the area to remove dirt, oil, or cosmetic products.

2. Apply a Thick Layer: Spread a generous amount of gel evenly over the affected area. Do not rub in.

3. Cover with Occlusive Dressing: Use plastic wrap or a sterile dressing to keep the gel in contact with the skin and enhance absorption.

4. Leave in Place: For most uses, a waiting period of 30 to 60 minutes is recommended. Unless instructed otherwise, wait up to two hours for deeper numbness.

5. Remove and Clean: After the required time, remove the dressing and wipe off excess gel before proceeding with the procedure.

Recommended Dosage

• Adults: Up to 10 grams on 100 cm² of skin.

• Children (over 3 months): Dosage varies based on weight and area of application. Always consult a healthcare provider.

• Maximum Application Time: Typically should not exceed 2 hours in adults and 1 hour in children.

Never exceed the prescribed dosage or use it over large body areas unless under medical supervision.

Precautions

• For External Use Only: Do not ingest or apply inside the nose, mouth, ears, eyes, or genitals unless directed by a physician.

• Avoid Broken Skin: Application to open wounds may increase systemic absorption, raising the risk of toxicity.

• Monitor for Reactions: If you experience dizziness, blurred vision, drowsiness, or difficulty breathing, stop using the product and seek immediate medical attention.

• Infants and Small Children: May be more susceptible to adverse effects such as methemoglobinemia; use with caution.

Possible Side Effects

Like all medications, Lidocaine-Prilocaine Gel can cause side effects, though not everyone will experience them.

Common Side Effects:

• Redness or slight discomfort where the application was made

• Numbness or tingling that may last longer than expected

• Temporary skin whitening or discoloration

Less Common but Serious Side Effects:

• Allergic reactions (itching, swelling, hives, rash)

• Dizziness or confusion

• Blue or gray lips, fingertips (signs of methemoglobinemia)

• Irregular heartbeat or fatigue (indicative of systemic absorption)

Discontinue use and consult a doctor if severe side effects occur.

Drug Interactions

Lidocaine-Prilocaine Gel may interact with:

• Other Local Anesthetics: Increased risk of systemic toxicity.

• Blood Pressure Medications: May affect heart rhythm and blood flow.

• Antiarrhythmic Drugs: Combined use may amplify effects on the heart.

• Nitrates and Sulfonamides: Increase risk of methemoglobinemia when used with prilocaine.

Always inform your healthcare provider about all medications and supplements you are taking.

Storage Instructions

• Keep out of direct sunlight and store in a cool, dry location.
• When not in use, keep the cap firmly closed.

• Do not freeze.

• Keep out of reach of children and pets.

Advantages of Lidocaine-Prilocaine Gel

1. Dual-Action Formula: To optimize numbing effectiveness, lidocaine and prilocaine cooperate.

2. Wide Application Range: Suitable for medical, cosmetic, and personal use.

3. Fast-Acting: Begins to numb the skin in just 30 minutes.

4. Long-Lasting Effect: Provides relief for up to two hours depending on application.

5. Non-Invasive: Applied topically without the need for injections.

6. Ease of Use: Comes in a convenient, portable tube with simple application instructions.

Who Should Use This Product?

• Healthcare Providers: For use in outpatient or in-clinic procedures requiring skin anesthesia.

• Tattoo and Piercing Artists: To reduce discomfort and enhance customer satisfaction.

• Cosmetic Technicians: For treatments like microneedling, fillers, or chemical peels.

• Parents: To ease anxiety during children’s immunizations or minor injuries.

• Individuals: For at-home hair removal or pain relief from minor skin irritation.

Conclusion

Lidocaine-Prilocaine Gel 10 gm is a reliable, fast-acting and safe solution for individuals seeking local anesthetic relief from painful or uncomfortable skin-related procedures. Its combination of lidocaine and prilocaine offers a balanced and effective approach to topical anesthesia, with widespread applications in medical, dental, cosmetic, and personal care settings.

By ensuring both quick onset and sustained relief, this gel significantly improves patient comfort and procedural outcomes. Whether you’re a medical professional or a first-time user, Lidocaine-Prilocaine Gel stands as a trusted option to numb pain and make procedures more manageable and less stressful.