Ivermectin 18 mg

Overview

A potent antiparasitic drug, ivermectin 18 mg, is used to treat a variety of human parasitic illnesses. It belongs to the class of medications known as anthelmintics and is effective against both internal parasites (like intestinal worms) and external parasites (such as mites and lice).

This 18mg formulation provides a higher dose of Ivermectin, typically prescribed for larger body weights, severe infections, or when lower-dose treatments are ineffective. It is commonly used to treat conditions such as strongyloidiasis, onchocerciasis, scabies, head lice, and other nematode infections.

The drug has been extensively studied and safely used worldwide for over three decades, and is included in the World Health Organization’s List of Essential Medicines due to its efficacy and safety.

Product Information

• Generic Name: Ivermectin

• Brand Name: Varies (e.g., Iverheal, Stromectol, etc.)

• Strength: 18mg

• Form: Oral Tablet

• Drug Class: Antiparasitic / Anthelmintic

• Packaging: Typically available in blister packs (10 tablets per strip)

Composition

Each tablet of Ivermectin 18mg contains:

• Active Ingredient: Ivermectin 18 milligrams

• Magnesium stearate, lactose, microcrystalline cellulose, and additional excipients (may vary by manufacturer)

What Is Ivermectin 18mg Used For?

1. Strongyloidiasis

A parasitic infection of the intestines caused by the roundworm Strongyloides stercoralis. Ivermectin is the first-line treatment, effectively killing larvae and adult worms.

2. Onchocerciasis (River Blindness)

Caused by the filarial worm Onchocerca volvulus, which leads to severe itching, rashes, and in chronic cases, blindness. By eliminating microfilariae, ivermectin 18 mg lessens symptoms and transmission.

3. Scabies

Sarcoptes scabiei is a mite that causes this infectious skin disease. Ivermectin 18mg helps eliminate mites and alleviate itching and skin rashes.

4. Pediculosis (Head Lice)

Ivermectin is effective in killing lice and their eggs, making it a good option for resistant or recurring cases.

5. Filariasis (Elephantiasis)

An infection by Wuchereria bancrofti or related worms that cause swelling in limbs. Ivermectin is often combined with other antiparasitics for comprehensive treatment.

6. Cutaneous Larva Migrans

A skin infection caused by hookworm larvae. Ivermectin rapidly eliminates the invading parasites.

Mechanism of Action

Ivermectin works by binding to glutamate-gated chloride channels found in the nerve and muscle cells of invertebrates (parasites). This binding causes the parasite to become paralyzed and die by increasing the cell membrane’s permeability to chloride ions.

Importantly, Ivermectin does not readily cross the blood-brain barrier in humans, which contributes to its favorable safety profile.

Dosage and Administration

Standard Guidelines:

• Route: Oral

• Timing: Take on an empty stomach with a full glass of water (at least 1 hour before or 2 hours after food).

• Dosage: Varies by infection type and body weight. Typically calculated at 150–200 mcg/kg of body weight. An 18mg tablet may be prescribed for higher weight groups or severe infections.

Examples by Condition:

• Strongyloidiasis: One dosage, maybe repeated in two weeks.

• Scabies: Two doses, 1 week apart.

• One dose every six to twelve months for onchocerciasis.

• Lice: May require repeat dose after 7–10 days.

Note: Always follow your doctor’s specific dosing instructions. Never self-medicate.

Key Benefits of Ivermectin 18mg

• High-Potency Treatment: Suitable for more severe or resistant infections.

• Broad Spectrum: Effective against a wide variety of parasites.

• Rapid Action: Begins working within hours; most patients experience relief within 24–48 hours.

• Convenient Dosing: Usually requires only one or two doses for treatment.

• Well-Tolerated: Proven safe for decades of use worldwide.

• Reduces Transmission: By killing larvae and eggs, it reduces spread in communities.

Who Can Take Ivermectin 18mg?

Indicated For:

• Adults and adolescents weighing over 60 kg

• Patients with moderate to severe parasitic infections

• Individuals who do not respond to lower doses of Ivermectin

Not Recommended For:

• Children under 15 kg or under 5 years of age (unless prescribed)

• Pregnant or breastfeeding women (unless the benefit outweighs the risk)

• Patients with meningitis, severe liver disease, or immune compromise, without a physician’s guidance

Precautions and Warnings

Before Taking Ivermectin 18mg:

• Inform your doctor if you:

  • Are pregnant or planning pregnancy

  • Are breastfeeding

  • Have liver or kidney disease

  • possess a history of neurological conditions or seizures

  • Are on other medications, especially anticoagulants or sedatives

  • Have weakened immunity

Alcohol Use:

Avoid alcohol as it can increase drowsiness and may interact with the drug’s metabolism.

Possible Side Effects

Common (usually mild and temporary):

• Headache

• Dizziness

• Nausea

• Diarrhea

• Fatigue

• Mild skin rash

• Muscle aches

Less Common but Serious:

• Allergic reactions (hives, swelling, difficulty breathing)

• Vision disturbances

• Chest pain

• Low blood pressure

• Fever and swollen lymph nodes (in onchocerciasis)

• Seizures (rare)

Seek immediate medical attention if any severe side effects occur.

Drug Interactions

Ivermectin 18mg may interact with:

• Warfarin – increases bleeding risk

• Barbiturates or Benzodiazepines – may increase sedation

• HIV medications

• Certain antibiotics or antifungals

• Immunosuppressants

Provide your doctor with a full list of medications and supplements.

Storage Instructions

• Store at room temperature (15°C to 30°C / 59°F to 86°F)

• Keep in a dry, cool place away from sunlight

• Do not freeze

• Keep out of reach of children and pets

• Do not use expired medication

Overdose Information

Symptoms of Overdose:

• Tremors

• Confusion

• Visual disturbances

• Seizures

• Difficulty breathing

If overdose is suspected, seek emergency medical care immediately.

FAQs – Frequently Asked Questions

1. How soon does Ivermectin 18mg work?

Relief may begin within 24–48 hours, though full recovery may take a few days to a week depending on the infection.

2. Can Ivermectin 18mg treat COVID-19?

Ivermectin is not officially approved for COVID-19 treatment. Do not use it unless prescribed for off-label use by a qualified physician.

3. Can Ivermectin 18mg be taken daily?

No. Ivermectin is not meant for daily use. It is typically given as a single or spaced-out dose, depending on the infection.

4. Is Ivermectin 18mg safe during pregnancy?

Use during pregnancy should be avoided unless prescribed by a doctor. Discuss risks and benefits with your healthcare provider.

5. What happens if I miss a dose?

Take it as soon as you remember. If it’s near the time for your next dose, skip the missed one. Do not double dose.

Conclusion

Ivermectin 18mg is a high-strength antiparasitic medication designed to tackle moderate to severe infections that may not respond to lower doses. With its broad-spectrum activity, fast action, and convenient oral dosing, it is a trusted choice in managing parasitic conditions around the world.

Whether you’re suffering from scabies, intestinal worms, or skin-related parasitic issues, Ivermectin 18mg offers an effective and reliable solution. However, it should always be taken under medical supervision, as dosing and safety need to be tailored to individual health needs.