

Hydroxyurea Capsules IP 500 mg
$70.00 – $350.00
SKU : N/A
Category : General
Hydroxyurea Capsules IP 500 mg treat various cancers and sickle cell disease. They help reduce tumor growth and prevent painful crises by boosting fetal hemoglobin.
Hydroxyurea Capsules IP 500 mg are a trusted oral medication used to manage a range of serious health conditions, including sickle cell disease, leukemia, polycythemia vera, essential thrombocythemia, and certain cancers. This formulation offers a balanced approach of strength and flexibility, supporting long-term therapy while maintaining patient convenience.
What Is Hydroxyurea?
An antimetabolite utilized in hematology and oncology is hydroxyurea. It works by disrupting the DNA production pathway in fast-dividing cells, effectively slowing the growth of abnormal cells in the bone marrow and cancerous tissues. Additionally, it stimulates the production of fetal hemoglobin in patients with sickle cell disease, offering significant relief from painful episodes and reducing the need for blood transfusions.
Who Can Benefit?
Hydroxyurea 500 mg capsules are prescribed for several conditions:
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Sickle Cell Disease: Reduces the frequency and severity of painful crises and lowers transfusion needs.
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Chronic Myelogenous Leukemia (CML): Helps stabilize white blood cell counts when used alone or alongside targeted therapies.
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Polycythemia Vera: Controls elevated red blood cell levels, helping to prevent blood clots.
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Essential Thrombocythemia: Regulates excessive platelet counts to reduce clotting risk.
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Head and Neck Cancers: Often combined with radiation therapy to boost treatment effectiveness.
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Psoriasis (off-label): Used in select cases when other treatments are not tolerated or effective.
How It Works
The enzyme ribonucleotide reductase, which is essential for the synthesis of DNA, is inhibited by hydroxyurea. By blocking this process, it reduces the proliferation of abnormal cells. In sickle cell disease, the drug increases fetal hemoglobin, which improves red blood cell flexibility and reduces complications. In cancers and blood disorders, this DNA-targeted strategy helps manage abnormal cell growth with oral dosing.
Dosage Guidelines
The ailment and each person’s reaction determine the dosage. Common regimens include:
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Sickle Cell Disease: 15 mg/kg daily, with potential increase to 35 mg/kg depending on blood counts.
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CML and Polycythemia Vera: Typically 20–30 mg/kg daily, adjusted based on laboratory results.
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Essential Thrombocythemia: About 15 mg/kg daily, tailored to maintain safe platelet levels.
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Head & Neck Cancer: High-dose schedule alongside radiation—often 80 mg/kg every third day.
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Psoriasis: Up to 1,000–1,500 mg per day in divided doses.
Always follow your doctor’s prescription and check blood counts regularly for safe and effective dosing.
Key Benefits
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Oral Convenience – Capsule form allows at-home dosing—no need for hospital visits for infusions.
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Proven Effectiveness – Demonstrated success in managing blood disorders and enhancing cancer treatment outcomes.
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Flexible Dosing – Easily adjusted by doctors based on lab results and patient progress.
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Long-Term Use – Well-established safety record supports sustained treatment under medical supervision.
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Quality of Life Improvements – Fewer painful episodes, better disease control, and fewer hospital visits improve daily living.
Safety and Side Effects
Common Side Effects:
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Mild nausea or stomach upset
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Constipation or diarrhea
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Fatigue or headaches
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Skin dryness or mild rash
Serious Side Effects:
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Bone marrow suppression: Low white cells or platelets, increasing risk of infection or bleeding.
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Kidney or liver impairment: May occur without proper monitoring.
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Skin sensitivity: Increased sun sensitivity and rare skin changes with long-term use.
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Rare malignancies: Long-term use may slightly elevate rates of secondary cancers; monitoring is essential.
If you experience fever, prolonged bleeding, persistent fatigue, or unusual bruising, contact your doctor promptly.
Precautions and Monitoring
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Regular Lab Tests – Blood counts, liver function, and kidney tests at least every 4–6 weeks.
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Maintaining renal function and medication removal requires strict hydration.
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Sun Protection – Use sunscreen and cover up outdoors.
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Glove Use in Handling – To avoid skin exposure, wash hands after capsule contact.
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Pregnancy & Fertility – Effective contraception is required during treatment; men and women should plan accordingly.
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Avoid Live Vaccines – While on treatment, consult your healthcare provider before vaccination.
Drug Interactions
Hydroxyurea may interact with certain medications, especially:
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Bone marrow suppressants, like chemotherapy agents
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Nephrotoxic drugs, which may challenge kidney function
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Photosensitizing medications – increase sun sensitivity
Always review your medication list with your doctor or pharmacist.
Patient Guidance Tips
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Follow exactly as prescribed—do not skip or double doses.
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Maintain hydration throughout treatment.
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Attend all lab and doctor visits for safe dosage adjustments.
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Practice sun safety consistently.
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Monitor for symptoms like fever, infection signs, or unusual bleeding.
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Use gloves if handling capsules without swallowing immediately.
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Discuss fertility plans with your doctor well in advance.
Storage Information
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Store at room temperature, away from moisture and sunlight (15–30 °C or 59–86 °F).
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Keep capsules in the original container and out of reach of children.
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Dispose of unused capsules safely after expiration.
Why Choose MedicoEase?
At MedicoEase, you get:
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Genuine medications from trusted manufacturers
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Affordable pricing and bulk-saving options
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Super-fast, discreet delivery
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Dedicated customer care, with knowledgeable support on dosing and product use
Final Thoughts
Hydroxyurea Capsules IP 500 mg offer an efficient and effective treatment option for a variety of serious conditions. With convenient oral dosing, customizable regimens, and strong clinical backing, they empower both patients and doctors in disease management. Under careful medical monitoring and adherence to safety guidelines, hydroxyurea is a reliable partner in improving quality of life and controlling chronic illness.
Choose MedicoEase for affordable, quality medications backed by support and care. Allow us to assist you in maintaining your treatment objectives.
Quantity Value |
100 capsules ,1000 capsules ,200 capsules ,300 capsules ,400 capsules ,500 capsules |
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