Forcan 200 mg

$13.50$850.00

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Quantity ValuePriceQuantity 
10 Tablet/s$13.50
30 Tablet/s$36.00
50 Tablet/s$58.50
100 Tablet/s$110.00
200 Tablet/s$200.00
300 Tablet/s$285.00
500 Tablet/s$450.00
1000 Tablet/s$850.00

Forcan 200 mg is an effective antifungal medication used to treat fungal infections of the skin, lungs, mouth, throat, and vagina by stopping fungal growth.

Description

Forcan 200 mg is a powerful antifungal medication formulated with Fluconazole, an active pharmaceutical ingredient that belongs to the triazole class of antifungals. Forcan 200 mg is trusted globally for its broad-spectrum activity against a wide range of fungal infections affecting the skin, mucous membranes, internal organs, and systemic circulation. This medication is widely prescribed by physicians to both immunocompetent and immunocompromised individuals for treating various types of fungal infections, particularly those caused by Candida and Cryptococcus species.

Forcan 200 mg is available in tablet form for oral administration, ensuring ease of use and high bioavailability. The medication exerts a fungistatic or fungicidal effect, depending on the concentration and the fungal strain involved, making it suitable for mild, moderate, and even some severe fungal infections.

Composition

  • Active Ingredient: Fluconazole – 200 mg

  • Excipients: Pharmaceutical-grade inactive ingredients that support tablet formation, stability, and absorption.

Mechanism of Action

Fluconazole, the active compound in Forcan 200 mg, works by inhibiting the fungal cytochrome P450 enzyme 14α-demethylase, which is vital for converting lanosterol to ergosterol. Ergosterol is a key component of fungal cell membranes. When this synthesis is disrupted, the fungal cell membrane becomes dysfunctional, resulting in leakage of essential intracellular components, inhibition of growth, and ultimately the death of the fungal cell.

This targeted mode of action ensures minimal impact on human cells while effectively halting fungal replication and colonization.

Therapeutic Uses and Indications

Forcan 200 mg is indicated for a wide array of fungal infections, making it a versatile and essential antifungal agent in both general and specialized medical practice. Its primary indications include:

1. Oropharyngeal Candidiasis

Commonly known as oral thrush, this condition causes white patches inside the mouth or throat. Forcan helps eliminate Candida albicans and related species that cause this infection.

2. Esophageal Candidiasis

More severe than oral thrush, this infection affects the esophagus and may cause difficulty in swallowing. Forcan 200 mg is effective in clearing the infection and relieving symptoms.

3. Vaginal Candidiasis

Also known as a yeast infection, this affects the vaginal area and is associated with itching, discharge, and discomfort. Forcan provides quick and long-lasting relief, often with just a few doses.

4. Systemic Candidiasis

Infections affecting the bloodstream and internal organs. Forcan’s systemic activity makes it a first-line option in such life-threatening conditions.

5. Cryptococcal Meningitis

A serious fungal infection of the membranes surrounding the brain and spinal cord, often seen in HIV/AIDS patients. Forcan 200 mg is widely used in both induction and maintenance therapy.

6. Dermatophytosis

Infections of the skin, hair, and nails such as athlete’s foot, jock itch, and ringworm. Forcan treats the root fungal cause and prevents recurrence.

7. Fungal Prophylaxis

Used to prevent fungal infections in immunocompromised patients undergoing chemotherapy, organ transplantation, or suffering from AIDS.

Dosage and Administration

The dosage of Forcan 200 mg is individualized based on the type, severity, and location of infection, along with patient factors such as age, renal function, and immune status.

Common dosing patterns:

  • Oropharyngeal candidiasis: 200 mg on day 1, then 100 mg daily for 7–14 days.

  • Esophageal candidiasis: 200 mg on day 1, then 100–200 mg daily for 2–3 weeks.

  • Systemic candidiasis: 400 mg on day 1, followed by 200–400 mg daily.

  • Cryptococcal meningitis (acute phase): 400 mg daily for 10–12 weeks.

  • Vaginal candidiasis: A single dose of 150 mg is often sufficient, but 200 mg may be used in recurrent cases.

  • Prophylaxis: 200–400 mg once daily depending on risk assessment.

Administration Tips:

  • Can be taken with or without food.

  • Should be swallowed whole with a glass of water.

  • It is important to complete the full course even if symptoms resolve early to avoid resistance and recurrence.

  • Maintain consistent timing each day for optimal therapeutic levels.

Pharmacokinetics

  • Absorption: Rapid and nearly complete oral absorption with a bioavailability of over 90%.

  • Peak Plasma Levels: Reached within 1–2 hours after ingestion.

  • Half-Life: Approximately 30 hours, allowing for once-daily dosing.

  • Excretion: Primarily renal (80% unchanged in urine), necessitating dose adjustment in patients with renal impairment.

Contraindications

  • Known allergy or hypersensitivity to fluconazole or other azole antifungals.

  • Co-administration with drugs known to prolong QT interval such as cisapride.

  • Use in patients with severe hepatic dysfunction unless strictly monitored.

Precautions and Warnings

  1. Liver Monitoring:

    • Risk of hepatotoxicity. Liver function tests are recommended before and during prolonged treatment.

  2. Renal Function:

    • Dosage adjustment may be necessary in renal impairment to avoid drug accumulation.

  3. Pregnancy and Lactation:

    • Not generally recommended unless benefits outweigh potential risks. High doses should be avoided in pregnancy.

  4. Cardiovascular Risk:

    • Can prolong QT interval; caution in patients with heart rhythm disturbances.

  5. Pediatric and Elderly Patients:

    • Dose must be carefully calculated based on body weight and kidney function.

Drug Interactions

Fluconazole can interact with several medications:

  • Warfarin: Increases bleeding risk due to heightened anticoagulant effects.

  • Oral hypoglycemics: Risk of hypoglycemia due to delayed metabolism.

  • Phenytoin and carbamazepine: Increased levels may cause toxicity.

  • Cyclosporine and tacrolimus: Increases serum concentrations.

  • Theophylline: Fluconazole slows the clearance, increasing side effects.

  • Rifampin: May decrease fluconazole levels, reducing effectiveness.

Patients must inform healthcare providers of all medications, including herbal and over-the-counter products, before starting therapy.

Side Effects

Common Side Effects:

  • Nausea

  • Headache

  • Abdominal discomfort

  • Diarrhea

  • Skin rashes

Rare but Serious Effects:

  • Liver enzyme elevation and jaundice

  • Seizures

  • QT prolongation and cardiac arrhythmias

  • Stevens-Johnson Syndrome or toxic epidermal necrolysis

  • Anaphylaxis

If any serious reaction occurs, treatment should be discontinued immediately, and medical attention should be sought.

Advantages of Forcan 200 mg

  • Broad antifungal spectrum

  • Convenient once-daily dosing

  • Excellent oral bioavailability

  • Effective in both superficial and systemic infections

  • Trusted by healthcare professionals globally

  • Available in multiple strengths for tailored therapy

Storage and Handling

  • Store in a cool, dry place below 30°C.

  • Protect from direct sunlight and moisture.

  • Keep out of reach of children.

  • Do not use if the tablet shows signs of damage or if the packaging is compromised.

Patient Guidance and Counseling

  • Do not skip doses or stop treatment early, even if symptoms improve.

  • Avoid alcohol during the treatment course.

  • Inform the doctor of any history of liver, kidney, or heart conditions.

  • Do not take antacids or other supplements simultaneously without medical advice.

  • Use effective contraception during treatment, especially for women of childbearing potential.

  • Report any adverse reactions, especially skin changes, fatigue, yellowing of the eyes, or dark urine.

Conclusion

Forcan 200 mg is a clinically proven antifungal solution designed to combat a wide range of fungal infections effectively and safely. Its active ingredient, fluconazole, has been extensively studied and is known for its strong antifungal efficacy, favorable safety profile, and broad utility across age groups and infection types. Whether used to treat a simple yeast infection or a complex systemic fungal illness, Forcan 200 mg delivers reliable results when taken as directed under professional medical supervision.

With once-daily dosing, rapid absorption, and robust therapeutic activity, Forcan 200 mg stands out as an essential antifungal in modern medicine, bringing relief to millions suffering from fungal infections worldwide.

Additional information
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