Afatinib 20 mg

Afatinib 20 mg is a novel oral therapy that occupies an important place in the management of advanced non-small cell lung cancer (NSCLC). belongs to the class of drugs known as EGFR inhibitors and is intended for those patients whose tumor cells have EGFR gene mutations. 

What Is Afatinib 20 mg?

Afatinib is an oral targeted therapy that prevents the activity of certain proteins that cause the growth and spread of cancer cells. It is mainly used to treat non-small cell lung cancer (NSCLC) in patients with an EGFR gene mutation, It is one of the new generations of drugs called tyrosine kinase inhibitors (TKIs), which target and block the signals that make the cancer cells grow uncontrollably.

Key Advantages of Afatinib 20 mg

✅ Targeted Therapy: Blocks the EGFR protein, which drives the growth of cancer cells.

✅ Effective in EGFR Mutant NSCLC: Particularly indicated for NSCLC patients with EGFR mutations.

✅ Improved Survival Rates: Slows cancer progression and enhances quality of life.

✅ Oral Administration: Convenient tablet format.

✅ Trusted by Oncologists: Highly prescribed for its performance in targeting specific mutations in cancer cells.

Medical Uses and Indications

Afatinib is primarily used to treat late-stage non-small cell lung cancer (NSCLC), the most common type of lung cancer. is for patients who have tumors that contain certain genetic mutations in the EGFR gene, such as those with the L858R mutation and deletions in exon 19. The mutations lead the EGFR protein to overexpress, and cancer cells proliferate uncontrollably.

Afatinib is normally prescribed for:

1. Advanced Non-Small Cell Lung Cancer (NSCLC)

Afatinib is highly effective against EGFR-mutant NSCLC. is administered as initial therapy in individuals who have yet to undergo chemotherapy and possess cancer cells that have EGFR mutations.

2. Metastatic NSCLC

In those whose cancer has progressed to the rest of the body, might be prescribed in order to help control disease progress and alleviate symptoms.

3. Adjuvant Therapy

In some cases, is used along with other treatments to prevent lung cancer from coming back after surgery or radiation.

How Does Afatinib Work?

Afatinib inhibits the epidermal growth factor receptor (EGFR), a protein that stimulates cancer cell growth and survival. In individuals who have mutations in EGFR, this protein tends to be overactive, leading to excessive cell growth and tumor formation.

Afatinib irreversibly binds to the EGFR and other related receptors, inhibiting their capacity to transmit signals that stimulate tumor cell growth. This specific inhibition slows or prevents cancer cell growth while avoiding as much harm to healthy, non-malignant cells. a tyrosine kinase inhibitor (TKI) that inhibits the phosphorylation (activation) of these receptors, thereby inhibiting the signaling pathways that lead to cancer cell survival and growth.

Dosage & Administration

Note: Always follow the exact dosage instructions provided by your healthcare provider. Do not alter your dosage without consulting a doctor.

Standard Adult Dose:

• Afatinib 20 mg once daily.
• It should be taken at the same time each day for consistency.
• Take the tablet with or without food. Swallow it whole with a glass of water. Do not chew or crush the tablet.
• If you forget to take a dose, just miss the missed dose and go back to taking the next dose at the regular time. Don’t take two doses at once.

Dose Adjustments:

Your doctor will change the dosage based on your ability to tolerate the medication or when side effects become a problem. The dose is 20 mg to 40 mg per day, depending on how an individual responds.

Side Effects

As with any drug, Afatinib 20 mg can have side effects. Some side effects are mild and manageable, but others need medical attention.

Common Side Effects:

• Diarrhea: The most frequent side effect of Afatinib. It is essential to control it early to prevent dehydration.
• Rash or Acne-like rash: Usually observed on the face, chest, or back.
• Nausea or vomiting: Can happen, particularly during the initial days of treatment.
• Mouth sores: Painful sores that occur within the mouth or throat.
• Fatigue: Excessive tiredness or weakness.

Severe Side Effects:

• Pneumonitis: Uncommon but severe lung inflammation that should be treated right away by a healthcare provider.
• Liver damage: Symptoms include skin or eye yellowing, dark-colored urine, and upper abdominal pain.
• Eye problems: Dry eyes, redness, or irritation.

In case any of the above serious side effects appear, call your healthcare provider immediately.

Precautions and Warnings

Before starting treatment with Afatinib, inform your doctor if you:

• Are allergic to Afatinib or any of the ingredients in the tablet.
• Have a history of lung disease or liver problems.
• Are pregnant, planning to become pregnant, or breastfeeding. Afatinib should not be used during pregnancy unless the benefits outweigh the risks, and it is not recommended while breastfeeding.
• Are now taking any other medications, such as over-the-counter medications or supplements. Afatinib can interact with other medications, such as antacids, antifungals, and antibiotics.

Drug Interactions

Afatinib can interact with other medications, which might make it work less well or increase the chance of side effects. Drug interactions can occur with:

• Rifampin: An antibiotic that can lower the effectiveness of Afatinib.
• CYP3A4 inducers/inhibitors: Drugs that impact liver enzymes can change the metabolism of Afatinib.

Always notify your healthcare provider of all the medications you are presently taking.

Storage Instructions

• Store Afatinib 20 mg at room temperature between 15°C and 30°C (59°F to 86°F).
• Store in a dry place, away from light and moisture.
• Keep out of reach of children.
• Do not use past expiration date printed on the package.

Why Choose MedicoEase for Afatinib 20 mg?

At MedicoEase, we offer 100% authentic, high-quality drugs at reasonable prices. When you purchase from us, you enjoy:

• Authentic and quality-approved products
• Secure and timely delivery
• Professional customer support for any questions
• Reasonable prices with seasonal offers

Order Afatinib 20 mg from our product page or contact our experts for more details.

Final Thoughts

Afatinib 20 mg Tablets are a cutting-edge, targeted therapy for the treatment of non-small cell lung cancer (NSCLC) with EGFR mutations. By inhibiting certain proteins that are responsible for the proliferation of cancer cells, Afatinib has the potential to greatly enhance treatment outcomes, reduce tumor growth, and improve the quality of life for patients.